Sava's shares lost 1.89% to close at 20.80 euro on Thursday, LJSE bourse data showed.
Insurer Zavarovalnica Triglav [LJE:ZVTG] lead the gainers, with shares advancing 0.85% to 35.80 euro.
The blue-chip SBITOP index ended 0.61% lower at 1,062.67 points, while the SBITOP TR index, which also tracks dividend distribution, fell 0.58% to 1,330.94 points on Thursday.
Total daily regulated marker turnover dropped to 1.1 million euro ($1.1 million) on Thursday from 1.3 million euro on Wednesday.
Drug maker Krka [LJE:KRKG] booked the largest turnover - of 501,202 euro. Its shares closed 1.27% lower at 93.40 euro.
($ = 1.0046 euro)