The new service is Wizz Air's third connection from Iasi to Great Britain and the company's twentieth overall from Iasi.
As of October 24, Wizz Air will fly from the southern city of Craiova to Birmingham on Tuesdays and Saturdays.
This is Wizz Air's second route from Craiova to Great Britain and its eighth from Craiova.
Earlier this month, Wizz Air announced that it is launching a new route from Romania's northwestern city of Cluj-Napoca to Liverpool in the UK, starting October 23.
In August, Wizz Air launched eight new routes from Romania's capital Bucharest - to Cagliari, Copenhagen, Bergen, Hamburg, Karlsruhe, Memmingen, Santorini and Mykonos.
In June, the air carrier announced that it will open on October 29 a base in the Romanian northeastern city of Bacau, its seventh in the country.
Wizz Air offers over 160 routes to 47 countries from ten airports in Romania.